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They both require pyridoxal-5-phosphate, the active form of vitamin B6, as a cofactor for their enzymatic activity [26, 27, 28]

doi: 10.3168/jds.2017-12935 136 WeissW

The UK regulator recommends that in adults weighing less than 50 kg, clinical judgement should be employed when prescribing oral paracetamol as these patients may be at increased risk of hepatotoxicity but does not specify a dose reduction

Additionally, water-soluble dendrimers can be prepared, in contrast to most polymers, via functionalizing the external shell with the help of hydrophilic groups or charged species