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This increased SF penetration was not reduced in the free-ibuprofen and the non-targeted nanocarrier groups, only the 3-PLG-ibu-A-GSH treatment decreased the elevated permeability in a statistically significant way (Fig

In hypobaric hypoxia, respiratory metabolism is enhanced, increasing reactive oxygen species (ROS) radicals in the electron transport chain complex III, which inactivates PHD, and the inactivated PHD can affect the stability of HIF-1 protein through the phosphorylation pathway (Bw et al., 2013)

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La mlanine a un rle protecteur important, car elle absorbe une partie des rayons UV pour prserver lADN des cellules