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Following the Phase Ib readout, Zealand expects to initiate a mid-stage study for petrelintide imminently, with data expected by the end of 2025 or early 2026, as per the Leerink note

Ann Clin Transl Neurol (2018) 5(10):121121

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And it is interesting to note that the intrinsic pathway is mainly induced by blocking the expression or activity of intracellular phospholipid peroxide scavenging systems [e.g., glutathione peroxidase 4 (GPX4)], by excessive phospholipid peroxidation, or by a dysregulation of ferric ion homeostasis (194)