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The absence of glucose effects means dosing does not need to be coordinated with meals or adjusted for diabetic status, and there are no concerns about timing relative to insulin sensitivity

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RAB22A activates phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (PI3K2A) to produce phosphatidylinositol 4-phosphate (PI4P) that recruits ATG12-ATG5-ATG16L1

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