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Smokers are therefore significantly exposed to oxidative stress, and this may be one of the pathways through which smoking contributes to the development of disease

Biomed Pharmacother 101:656662 Dufour M, Faes S, Dormond-Meuwly A, Demartines N, Dormond O (2014) PGE2-induced colon cancer growth is mediated by mTORC1