Finally, its worth noting that aging itself disrupts circadian rhythms, but conversely, experimental circadian disruption (e.g., chronic jet-lag in animal models) can shorten lifespan and induce phenotypes of premature aging ( 8 Limitations and evidence gaps Key gaps include limited long-term randomized clinical trials, variability in intervention timing and dosing, and insufficient stratification by age, sex, chronotype, and comorbidities
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Zandbergen 2 , Susanne Olthuis 3 , Wim Van Zwam 4 , Jeannette Hofmeijer 5 , Bart Emmer 6 , Arnolt-Jan Hoving 6 , Robert van Oostenbrugge 7 , Heleen den Hertog 8 1 Isala Hospital Zwolle, Zwolle, Netherlands, 2 Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands, Rotterdam, Netherlands, 3 Department of Neurology, Maastricht University Medical Center+, Maastricht, The Netherlands, Maastricht, Netherlands, 4 Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, Maastricht, The Netherlands, Maastricht, Netherlands, 5 Department of Clinical Neurophysiology, University of Twente, Enschede, and Department of Neurology, Rijnstate, Arnhem, The Netherlands, ENSCHEDE, Netherlands, 6 Department of Radiology and Nuclear Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands, Amsterdam, Netherlands, 7 Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands, Maastricht, Netherlands, 8 Department of Neurology, University Medical Center Groningen, The Netherlands, Groningen, Netherlands Background and Aims: Hyperglycemia is common in ischemic stroke
Supporting thyroid health with vitamins 14 Nov 2025 Supporting Thyroid Health with Vitamins and Minerals
