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Am J Physiol 280:C415422 Myllyharju J, Koivunen P (2013) Hypoxia-inducible factor prolyl 4-hydroxylases: common and specific roles

216 In addition, PRMT4-catalyzed asymmetric dimethylarginine (ADMA) has been reported to bind to NOS as a ligand, leading to NOS dysfunction, resulting in decreased cerebral blood flow and aggravating AD, which can be reversed by inhibition of PRMT4

So it's no surprise that a lot of our colleagues, who were probably classically trained like we were, have a hard time wrapping their brains around so much of what you just shared, which was really valuable information

doi: 10.1016/j.ajpath.2017.03.011 38 BerthonB