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The mechanisms are well-characterized: angiogenesis, collagen synthesis, inflammation reduction, and neuroprotection

Most evidence remains theoretical rather than robustly validated

Published findings describe effects on genes associated with antioxidant response (Nrf2 pathway), DNA repair mechanisms, ubiquitin-proteasome pathway components, and inflammatory signaling cascades

What This Series Has Been Building Toward We started with GLP-1s because they offered the most visible entry point: a medication the public already knew, whose most important effects turned out to be something other than what the public conversation assumed