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7 Conclusion Tobacco microorganisms play a crucial role in enhancing tobacco quality, which represent a diverse group, primarily consisting of bacteria and fungi with marked metabolic capabilities, including amino acid metabolism, carbohydrate metabolism, vitamin metabolism, and the biosynthesis of flavors and fragrances

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ASA works to reduce the synthesis of prostaglandin E2 and pro-inflammatory cytokines by inhibiting the cyclooxygenase COX-1 and COX-2 enzymes (Israel et al., 2021)

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