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By the time Samols returned to the Royal Free Hospital in 1964, many researchers had begun to intensify their efforts to characterise, identify and purify substances in the intestine released in response to eating that helped to stimulate insulin secretion

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It is difficult to give a one-size-fits-all answer to the question, "How long does it take for B12 injections to work." It is possible for some individuals to notice the improvement in their symptoms right away, whereas, for others, it may take additional injections to achieve optimal health