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The clinical benefit was evaluated by comparing parameters qualifying the response to treatment (change from baseline UPDRS motor score) estimated for SC and SL administration over the interval 0 to 90 min post-dose using trial simulations

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Studies document enhanced angiogenesis with increased blood vessel formation in wound beds, providing better oxygen and nutrient delivery to healing tissues

Topical NSAIDs (such as ibuprofen gel) offer localised pain relief with minimal systemic absorption and are recommended by NICE as first-line for localised joint pain