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A summary of these key results is found in Fig

UC involves the colonic mucosa in a continuous distribution from the anal verge to all or part of the colon CD involves transmural patchy inflammation with intervening normal mucosa and can occur anywhere in the gastrointestinal tract from the mouth to the anus Indeterminate colitis has features of UC and CD EIMs can be present in all forms of IBD Epidemiology Onset of IBD is most frequent among adolescents, with a peak incidence between ages 15 and 25 years

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[54] Ovalocytes are also typically seen on the blood smear, and a pathognomonic feature of megaloblastic anemias (which include PA and others) is hypersegmented neutrophils