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Always take a thorough medical history, check for known allergies (particularly to cobalt or cobalamin compounds), and make sure your emergency protocols are current

Vitamin B12 injection effects can include: Soreness or slight bruising where the needle goes in A warm feeling right after the injection Mild headache in some people, which usually passes quickly Rare allergic reactions, which is why a health check happens first Vitamin B12 injection painful is a common worry, but most people describe it as a quick pinch rather than anything severe

In some cases, intramuscular injection may be recommended by a provider

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