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B12 may further support this process by promoting the proper functioning of insulin-producing cells in the pancreas

(4) Baar MP, Brandt RMC, Putavet DA, Klein JDD, Derks KWJ, Bourgeois BRM, Stryeck S, Rijksen Y, van Willigenburg H, Feijtel DA, van der Pluijm I, Essers J, van Cappellen WA, van IJcken WF, Houtsmuller AB, Pothof J, de Bruin RWF, Madl T, Hoeijmakers JHJ, Campisi J, de Keizer PLJ

In addition, acetaldehyde is highly reactive and capable of adducting proteins and lipids that, in turn, initiate a series of deleterious cellular events

This DMF concentration didnt reduce cell viability under non-BSO pretreatment condition and reduced cell viability less than 5% under BSO pretreatment condition (Supplementary Figure S2)