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Three phases of detoxification:[ref] Phase I (bioactivation transformation) involves breaking apart large toxins and converting them into polar molecules

Some arrhythmias, such as ventricular fibrillation , can be immediately life threatening because they impact the pumping action of the heart substantially enough to disrupt blood supply to the body, potentially leading to sudden cardiac death , one of the most common causes of death in the United States (Estes 2011

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