Nervous system disorders Uncommon: Headache Not known: Convulsions*, Dizziness Heart disease Not known: Palpitations Vascular pathologies Uncommon: Hypertension, Hypotension Respiratory, thoracic and mediastinal pathologies Not known: Dyspnea Gastrointestinal disorders Common: Vomiting, Nausea, Diarrhea, Abdominal pain Uncommon: Dysgeusia, Dyspepsia, Dry mouth Skin and subcutaneous tissue disorders Uncommon: Abnormal skin odor ** Not known: Itching, Skin rash Musculoskeletal and connective tissue disorders Uncommon: Muscle spasms Not known: Myasthenia***, Muscle tension Systemic disorders and conditions related to the administration site Uncommon: Chest pain, Feeling abnormal, Pyrexia, Injection site reaction**** Diagnostic tests Uncommon: Increased blood pressure Very rare: Increased INR*****
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The functional expansion of Nrf2 in proliferating cells directs the enhancement of anabolic metabolism, maintains redox homeostasis and further promotes the activation of PI3KAkt signaling, suggesting the presence of positive feedback between Nrf2 and the PI3KAkt pathway in proliferating cells (Figure 9)
Intermittent versus daily calorie restriction: which diet regimen is more effective for weight loss