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A key supporting study was retracted due to data fabrication, and the related prodrug fosgonimeton saw adverse events in clinical trials

Mast cells are exquisitely sensitive to environmental stimuli, including toxicants, and play a central role in initiating inflammatory responses

They should be kept away from light and must not be repeatedly frozen and thawed

These include: Tingling, numbness, or a 'pins and needles' sensation in the hands and feet Difficulty with balance and coordination Muscle weakness Memory problems, difficulty concentrating, or 'brain fog' Mood changes, including low mood or irritability Important: New or worsening neurological symptoms such as paraesthesia, gait disturbance, or cognitive change should be treated as urgent