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None of this changes the comparison for an existing smoker, but it is exactly why the consistent advice - ours and the NHS's - is that vaping is for adult smokers and current vapers only

For another, not all population groups respond to questions about loneliness in the same way (aka measurement invariance)

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Importantly, while caloric restriction has been hypothesized to hold preventive effects, malnutritionreported in up to 60% of patients with PDmay complicate this relationship, given its association with adverse health outcomes and poorer quality of life 57