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Researchers have also made significant strides in enhancing properties of GO through nitrogen doping

Nevertheless, long-term safety data, high-dose exposure effects, and use in vulnerable populations remain insufficiently characterized

In a randomized, double-blind, placebo-controlled study, 77 diabetic nephropathy patients were randomly assigned to receive pirfenidone at 1200 mg daily, pirfenidone at 2400 mg daily, or placebo for 54 weeks

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