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This finding suggests that cannabis-related bronchitic changes may primarily result from inflammatory or irritative processes rather than fixed structural damage, as evidenced by the reversibility of symptoms upon cessation

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Although some epigenetic changes induced by tobacco smoke appear to be stable and persist into childhood or even adulthood (39,43), it has been suggested that cessation of smoking, especially before or during early pregnancy, can reduce the extent of fetal exposure and limit epigenetic disruptions