Activation of NLRP3 inflammasome has been identified in endothelial cells when exposed to nicotine
So then we kind of made it a running gag
Some of the most common causes include: Not getting enough electrolytes in your diet, especially calcium, magnesium, and potassium Anorexia nervosa, an eating disorder Inflammation in your heart (myocarditis), the inner lining of your heart (endocarditis), or the sac that holds your heart (pericarditis) Infections, like strep throat, which can damage your heart valves Rheumatic fever or rheumatic heart disease (This may be another complication of strep throat.) Lyme disease, which is an infection you can get from a tick bite Chagas disease, which is an infection you can get from a kissing bug bite Certain medications, such as beta-blockers, calcium channel blockers, anti-arrhythmia drugs, narcotics, lithium, depressants, or cannabis Heart surgery, such as valve repair and replacement Radiation therapy Bradycardia Risk Factors Anything that increases your risk of having heart problems can increase your risk of bradycardia, such as: Older age High blood pressure Smoking Heavy alcohol use High levels of stress and anxiety Using recreational drugs, especially narcotics and cannabis (marijuana) Bradycardia Diagnosis Your doctor will likely diagnose you based on a physical exam and tests, such as: EKG
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