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While these enzymatic changes were not consistently evident in noticeable memory deficits, they indicate that NAC preserves cholinergic function by facilitating both the synthesis and breakdown pathways of ACh

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Vitamin B12 plays a role in breaking down fats, proteins, and carbohydrates, ensuring that the body efficiently uses the food it consumes for energy

Potential interventions include pharmacological agents ( e.g ., aminoguanidine, metformin, phenylthiazolidine, and pyridoxamine), dietary modifications ( e.g ., low-AGE diets), and regular physical exercise (81, 82)