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SB 202190 Pack Size:10 mM * 1 mL in DMSO Adagrasib covalently binds to KRAS

SKU: 9121361869

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Description

Adagrasib covalently binds to KRAS G12C at the cysteine at residue 12

ZBP1 regulates NLRP3 (nucleotide and oligomerization domain

of which PARP-1 (and to a lesser extent PARP-2) respond to DNA-strand breaks

Dasatinib (BMS-354825) is a highly potent

SB 202190 Pack Size:10 mM * 1 mL in DMSO Adagrasib covalently binds to KRASSB 202190 is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38 and p382, respectively. SB 202190 binds to the ATP pocket of the active recombinant human p38 kinase with a Kd of 38 nM. SB 202190 has anti cancer activity and rescued memory deficits. SB202190 induces autophagy.

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