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In the present study, a mouse model of chronic oxidative stress due to compromised de novo GSH synthesis (GCLM KO) 16 exhibited unexpected protection from chronic alcohol consumption-induced hepatotoxicity and steatosis

Antioxidants (radical scavengers) are protective substances for body cells that can prevent potentially damaging oxidation of cell structures by neutralising particularly aggressive chemical compounds

As previously mentioned, the role of HO-1 in cancer is quite controversial since this enzyme can behave either as an anti-tumour factor or as a pro-tumour one [56,57,89]