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In response to various stimuli, endolysosome damage leads to the formation of specific cellular elements via efficient LQC, which includes lysosomal repair, lysophagy, and lysosomal regeneration 26 (Fig

Peptide therapy and biologicals are not cheap

In a randomized, double-blind, placebo-controlled trial, daily supplementation with Lactobacillus plantarum ECGC 13110402 for 12 weeks in adults with moderate hypercholesterolemia resulted in a significant reduction in LDL cholesterol and hs-CRP compared to placebo, suggesting a direct benefit of probiotics on cardiovascular risk markers in humans (Zhou et al., 2023)

As we age, natural GH production declines, and the pituitary gland becomes less responsive to GHSs