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Biochemistry 40, 48114820

The administration of celecoxib, a selective COX-2 inhibitor, improved depressive behavior in experimental rats by altering age-dependent increases in the levels of proinflammatory cytokines and anti-inflammatory corticosterone in the hippocampus [138]

Thus, the aim of this review is therefore to provide a comprehensive and updated overview of AXs mechanistic actions in muscle metabolism, exercise performance, and obesity, with a special focus on emerging delivery strategies that translate its molecular potential into clinical bioefficacy

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