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GLP-1 was shown in an in vitro experiment to protect - cells from methylglyoxal-induced apoptosis, by improving mitochondrial function and suppressing prolonged activation of AMP-dependent protein kinase (AMPK) ( Upon glucose stimulation, the pancreatic -cells release insulin into the circulation from secretory granules, where it is temporarily stored, along with another short peptide called amylin (islet amyloid polypeptide

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Secondly, P can also enhance ROS production

FAD and FMN act as electron carriers in a number of oxidation-reduction (redox) reactions involved in energy production, cellular antioxidant function, and in numerous metabolic pathways