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Moreover, the combination of carboxymethylated chitosan and alginate is optionally used to assist in increasing the permeability of the active agent through the round window membrane

Yan H, Ma Y, Liu M, Zhou L

However, it would appear this is the case only in one very specific circumstance: That is, when doctor-prescribed vitamin B-12 is administered to treat pernicious anemia (via Pernicious Anemia Relief)