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2.4 Integration of gut, brain, and kidney signals The gut-brain-kidney axis is closely linked to the development and progression of several specific diseases, with each organ system influencing the others in ways that can exacerbate or mitigate these conditions, including CKD (Figure 2), hypertension, irritable bowel syndrome, and kidney stones

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Due to a lack of studies on PET-NaPs, our goal was to investigate if PET-NPs could trigger harmful effects on the cerebrum, cerebellum, and hippocampus of Swiss albino mice