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By not prioritizing enforcement against other flavored ENDS products in the same way as flavored cartridge-based ENDS products, the FDA has attempted to balance the public health concerns related to youth use of ENDS products with consideration regarding addicted adult cigarette smokers who may try to use ENDS products to transition away from combustible tobacco products, the agency stated, adding that cartridge-based ENDS products are most commonly used among youth

Other metals such as K, Ca, Ti, Cr, Mn, Fe, Zn, and the nonmetal Br have been recently identified in e-liquids [30,31]

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The amount of nicotine in the liquid can be the same or even more than the amount found in cigarettes