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Additionally, previous literature has identified various mechanisms of action for the aforementioned compounds, which disrupt membranes and nucleic acid synthesis, ultimately reducing extracellular polymeric substance secretion and the formation of biofilms 100

Researchers should note that more investigation is needed to fully comprehend this peptides mechanisms and effects

The docking also suggests that the interaction with HPV-16 E7 involves the same GSTP1 surface region that participates in homodimerization with a second GSTP1 molecule, as seen in the native enzyme homodimer in the Protein Data Bank (PDB) structure 1AQW (Figures 3B and 3C)