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Other peptides (BPC-157, GHK-Cu, Epitalon) have biological plausibility and animal data but lack human clinical validation

Internal transcribed spacers (ITS-1 and ITS-2) (218221) and ribosomal RNA gene (222) of nuclear ribosomal DNA, and cytochrome oxidase subunit 1 (cox1) (221, 223225), NADH dehydrogenase subunits (223, 226), and cytochrome b (221) of mitochondrial DNA are usually applied as target genes, while some other genes, including the long-terminal repeat of C

Rather than supplying GH directly, they trigger GH release through the bodys own mechanisms, maintaining the pulsatile secretion pattern and feedback inhibition that characterize normal physiology