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The cardiovascular effects (heart attacks and stroke) of smoke exposure happen within minutes and anyone who has risk factors like high blood pressure, cholesterol, weight or age is immediately endangered by secondhand smoke. About 9% of adults 18 and older in San Francisco are estimated to smoke, according to 2023 data from the Centers for Disease Control and Prevention

Specific protein 1 (Sp1) is a ubiquitous, stress-activated transcription factor in the nucleus that regulates genes involved in apoptosis and senescence [21]

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