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Tidal volume 6-8cc/(ideal body weight in kg): lung protective strategy Minute ventilation (respiratory rate multiplied by tidal volume): less than 115 mL/kg/min Allow increased expiratory time by decreasing I:E ratio (1:3 or 1:4 up to 1:5) Low PEEP (start approx 5 or 80% intrinsic PEEP) Start FIO2 at 100 percent then titrate downwards for SpO2 above 90% or PaO2 above 60 mmHg For more see EMRAP s vent strategy here: [6] Discuss disposition and discharge planning for an acute asthma exacerbation presenting to the ER Wise Cracks [1] What is delayed sequence intubation